John Wayne Casserole


John Wayne Casserole

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Recipe by Julia Pacheco Course: MainCuisine: AmericanDifficulty: Easy


Prep time


Cooking time




  • 1 lb ground beef

  • 1/2 white onion, diced

  • 1.5 tbs taco seasoning

  • 1/4 cup water

  • 1 can rotel

  • 1 can corn, drained

  • Bisquick Mixture
  • 2 cups Bisquick

  • 1 cup water

  • Creamy Mixture
  • 1/4 cup mayonnaise

  • 7.5 oz chive and onion cream cheese mixture

  • 1/8 tsp pepper

  • 1/8 tsp garlic powder

  • 1 cup shredded sharp cheddar cheese

  • 1 cup mozzarella cheese


  • Preheat oven to 325 degrease
  • To a skillet over medium heat add the ground beef and onion cook the beef thorough, once cooked remove any access grease then add in the taco seasoning, and water simmer for 3 minutes then add in the rotel, corn,
  • Now add the “bisquick mixture” into a bowl and stir until combined, you might need to add a little more water or bisquick until well combined.
  • Add the “creamy mixture” in a small bowl and whisk well.
  • Grease a 9×13 baking dish with non-stick spray then add the bisquick mixture in and spread it out evenly. Pour the ground beef mixture on top, spread the creamy mixture over the ground beef mixture then sprinkle with the cheeses. Bake for 40 minutes. Let sit for 10 minutes before enjoying. Top with your favorite taco toppings.

Recipe Video


  1. HUGE smiles at our house for this one. And it became a meal two-fer. I got started late trying to make this for lunch, and decided to just make a half recipe in an 8×8 pan for supper, using the other half of the meat/onion/Rotel mixture (before adding corn) as filling for lunchtime hardshell tacos. Continued on late in the afternoon with prep of the crust and creamy topping mixtures.

    My total prep time was longer because I did not want to go grocery shopping so chose to use a homemade taco-spice combo, a homemade Bisquick-equivalent (one that used butter) and an onion & chive cream cheese using ingredients on-hand, that started with a block of plain cream cheese.

  2. My wife and I were amazed at the taste of this dish. My wife does usually doesn’t like chilis but in this case she wanted seconds. We added sour cream as a side dip. Thank you for putting this recipe out for all to try.

  3. Jayne Savage

    I found you on YouTube and I’m so glad I tried this recipe! It is so easy and absolutely delicious. My husband loves it, too. This will definitely be a staple in our monthly menu rotation. I can’t wait to try more of your recipes. Thanks for sharing them!

  4. I love this recipe Thank you so much πŸ™‚
    Patty from the Pacific NW

  5. This is without a doubt, one of the most delicious and easy recipes I have ever made and eaten. Oh my gosh.
    The only thing I would suggest is make sure you keep the cheese separate until the end and do not include it in the creamy mixture….(like I did) and then just sprinkle it over the top right before you bake it. It is simply divine.

  6. Kimberly Estes

    This is one of my husbands most requested dinners! So delicious and filling! ((Just leave out the shredded cheeses from creamy mixture as those will go on top of casserole)) thank you for another delicious recipe 🀩

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